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What is Opana ER?

Opana ER, also available as Numorphan or Opana, is an opioid medication. It helps treat moderate to severe pain. Oxymorphone extended-release form is for around-the-clock treatment of pain or should not use-as-needed basis for pain.

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The use of opioid medications can cause addiction, overdose, or death.

How to take Opana ER?

The generic name of Opana ER is Oxymorphone hydrochloride 5mg. It is available in tablet forms and extended-release.

Only healthcare professionals who know the use of potent opioids for chronic pain management should prescribe you to take Opana ER.

It will help if you prefer using the lowest dosage for a short duration consistent with individual patient treatment objectives.

Doctors must initiate the dosing regimen for each patient according to their condition, considering the patient’s response, the severity of pain, risk factors regarding addiction, abuse, and misuse, and prior analgesic treatment experience.

The medical team should monitor patients for respiratory depression within the first 24 to 72 hours of the initial dosage and adjust the further doses accordingly.

Swallow the whole tablet with enough water to ensure complete swallowing instantly after placing it in the mouth rather than crushing, chewing, or dissolving it. Otherwise, it may result in the uncontrolled delivery of oxymorphone and lead you to overdose or death.

Take Opana ER capsule on an empty stomach, at least one hour before a meal or two hours after eating.

Administer this medicine orally after every 12 hours.

The initial dosage of Opana ER is an opioid analgesic is 5mg every 12 hours orally.

The starting dosage of Opana ER for non-opioid-tolerant patients is 5mg every 12 hours orally.

What to know before taking Opana ER?

Before taking this medicine, tell the doctor if you are allergic to it or other opioid pain medications (such as morphine, codeine, oxycodone) or different allergic reactions. It may contain inactive allergic reactions causing ingredients or other problems. To get more details, talk to your doctor or pharmacist.

Before using Opana ER, tell each of your medical healthcare providers about your medical history, especially if you have ever had:

  • Breathing problems (such as sleep apnea, asthma, COPD- chronic obstructive pulmonary disease);
  • Brain disorders (such as brain tumor, head injury, seizures);
  • Kidney disease;
  • Liver disease;
  • Gallbladder disease;
  • Mood swings or mental disorders (such as depression, confusion, suicidal thoughts)
  • Personal or family past of a substance use disorder (such as drug or alcohol addiction or overuse);
  • Stomach or intestinal problems (such as diarrhea due to infection, constipation, blockage, surgery, paralytic ileus);
  • Esophagus or colon cancer;
  • Pancreatitis (disease of the pancreas);
  • Difficulty swallowing;
  • Difficulty urinating due to enlarged prostate

This drug may cause dizziness or drowsiness. Alcohol or marijuana (cannabis) consumption can make you more drowsy or dizzy. Avoid driving a vehicle or performing any activity that requires alertness. Avoid consumption of alcoholic beverages.

Before going for surgery, tell the medical team about all the products you use (including herbal products, prescription, or nonprescription drugs).

Older adults are more likely to face severe side effects, especially dizziness, confusion, shallow breathing, drowsiness.

Tell the doctor about your pregnancy while using this medicine. It may cause harm to an unborn baby. Discuss the benefits and risks of taking Opana ER with your doctor.

It is still unknown whether it will pass into the breastmilk and harm a nursing baby or not. However, similar drugs to Opana ER pass into breastmilk and may cause undesirable effects on a nursing baby. Tell the doctor promptly if your baby develops trouble breathing, unusual sleepiness, or difficulty feeding.

What are the benefits of using Opana ER?

Opana ER helps relieve severe ongoing pain. Opana ER tablets manage chronic pain and only for people who are already on a regular schedule of potent opioids for a prolonged period.

These tablets are for breakthrough pain for people on the extended-release version. In comparison to other opioids, Opana ER has similar pain-relieving efficacy.

What are the side effects of Opana ER?

Common side effects of using Opana ER may include:

  • Nausea;
  • Headache;
  • Vomiting;
  • Dry mouth;
  • Constipation;
  • Dizziness;
  • Drowsiness;
  • Lightheadedness; or
  • Mild itching

To prevent constipation, drink enough water, eat dietary fiber, and exercise regularly.

Tell the doctor instantly if you have severe side effects, including:

  • Sleep apnea;
  • Mood swings or mental changes (such as confusion, agitation, hallucinations);
  • Vision changes;
  • Slow or rapid heartbeat;
  • Pain in stomach or abdomen;
  • Difficulty urinating;
  • Choking or gagging while taking this medicine; or
  • Signs of non-efficient functioning of adrenal glands such as unusual tiredness, loss of appetite, weight loss

It is not a complete list of side effects, and others may occur. Take medical help regarding side effects. Report side effects to FDA at 1-800-FDA-1088.

How Opana ER works?

Opana ER works by changing the way of body response to pain. Use of opioids with alcohol or other drugs may lead to fatal effects or cause drowsiness or slow breathing.

Oxymorphone’s immediate release indicates the relief of modern to severe pain, such as treating acute post-surgical pain. For the team’s chronic treatment, doctors should only consider long-term use if there is a significant clinical benefit to the patient’s therapy that outweighs any potential risk.

What to avoid while using Opana ER?

Avoid consumption of alcohol. It can lead to life-threatening side effects, or death could occur.

Avoid driving a vehicle or performing any hazardous activity until you know how Opana ER will affect you. Drowsiness or dizziness can cause falls, accidents, or severe injuries.